Just a random post to let you know that I have 0 issue with pico-8 on a M1 based computer.

I quickly tested Voxatron too. I had a crash on a first run for some reason but after that it worked. I didn't test extensively however.

It works on M1 if you have Rosetta installed. What if you don't want to use that?

Rosetta 2 installed by default on Big Sur and later.

https://forums.macrumors.com/threads/how-to-check-if-rosetta-2-is-installed-solved.2287833/